10% Enrofloxacin Txhaj
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Video
Pharmacological Action
Enrofloxacin yog broad-spectrum bactericidal agent rau fluoroquinolone tsiaj.Rau Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Porter's sepsis Bacteria, Staphylococcus aureus, Chlorosis, thiab lwm yam cuam tshuam rau cov kab mob zoo. thiab Streptococcus, thiab tsis muaj zog cuam tshuam rau cov kab mob anaerobic.Nws muaj cov nyhuv antibacterial pom tseeb ntawm cov kab mob rhiab heev.Cov tshuaj tua kab mob ua haujlwm ntawm cov khoom no yog txhawm rau tiv thaiv cov kab mob DNA gyrase thiab cuam tshuam nrog cov kab mob DNA replication, transcription thiab kho thiab recombination.Cov kab mob no tsis tuaj yeem loj hlob thiab rov ua dua qub thiab tuag.
Pharmacokinetics
10% Enrofloxacin Txhajyog sai thiab tag absorbed los ntawm intramuscular txhaj.Lub bioavailability ntawm cov khoom no yog 91.9% rau npua thiab 82% rau nyuj nyuj.Nws yog dav faib rau tsiaj thiab tuaj yeem nkag mus rau cov ntaub so ntswg zoo.Tsuas yog cov kua cerebrospinal, cov tshuaj concentration hauv yuav luag tag nrho cov ntaub so ntswg yog siab dua li cov ntshav plasma.Lub siab metabolism yog tsuas yog tshem tawm cov ethyl pawg ntawm 7-piperazine nplhaib los tsim ciprofloxacin, ua raws li oxidation thiab glucuronic acid binding.Nws yog tsuas yog tawm los ntawm ob lub raum (los ntawm lub raum tubular secretion thiab glomerular pom), thiab 15% ~ 50% yog tawm hauv cov zis hauv nws daim ntawv qub.Kev tshem tawm ib nrab-lub neej sib txawv heev ntawm ntau hom tsiaj thiab ntau txoj kev tswj hwm.Kev tshem tawm ib nrab-lub neej tom qab txhaj tshuaj intramuscular yog 5.9 teev rau nyuj, 9.9 teev rau nees, 1.5 mus rau 4.5 teev rau yaj, thiab 4.6 teev rau npua.
Kev sib tham
(1)10% Enrofloxacin txhaj tshuajyog siv ua ke nrog aminoglycosides lossis broad-spectrum penicillin, uas muaj cov nyhuv synergistic.
(2) Cov hlau hnyav xws li Ca2+, Mg2+, Fe3+ thiab Al3+ tuaj yeem chelate nrog cov khoom no thiab cuam tshuam rau kev nqus.
(3) Thaum ua ke nrog theophylline thiab caffeine, nws tuaj yeem txo cov ntshav plasma protein losis tswvyim dabtsi, nce qhov concentration ntawm theophylline thiab caffeine hauv cov ntshav, thiab txawm ua rau cov tsos mob ntawm kev lom theophylline.
(4) Cov khoom no muaj cov nyhuv inhibiting daim siab tshuaj enzymes, uas yuav txo tau cov clearance tus nqi ntawm cov tshuaj mas metabolized nyob rau hauv daim siab thiab ua rau kom cov ntshav concentration.
Muaj nuj nqi thiab siv
Fluoroquinolone tshuaj tua kab mob.Siv rau cov kab mob kab mob thiab kab mob mycoplasma hauv cov tsiaj nyeg thiab nqaij qaib
Dosage thiab kev tswj hwm
Intramuscular txhaj: ib koob, ib 1kg lub cev hnyav, 0.025ml rau nyuj, yaj, thiab npua;0.025 ~ 0.05ml rau dev, miv, thiab luav.Siv 1 mus rau 2 zaug hauv ib hnub rau 2 mus rau 3 hnub.
Kev phiv tshuaj
(1) Degeneration ntawm pob txha mos nyob rau hauv cov tsiaj me, cuam tshuam rau pob txha loj hlob thiab ua rau claudication thiab mob.
(2) Cov kab mob ntawm lub plab zom mov muaj xws li ntuav, tsis qab los noj mov, thiab raws plab.
(3) Cov kab mob ntawm daim tawv nqaij muaj xws li erythema, khaus, urticaria thiab photosensitivity.
(4) Kev ua xua, ataxia, thiab qaug dab peg muaj qee zaum pom hauv dev thiab miv.
Hebei Veyong kws tshuaj Co., Ltd, tau tsim nyob rau hauv 2002, nyob rau hauv Shijiazhuang City, Hebei xeev, Tuam Tshoj, ib sab ntawm lub peev Beijing.Nws yog ib lub tuam txhab loj GMP-certified veterinary tshuaj lag luam, nrog R & D, ntau lawm thiab muag khoom ntawm veterinary APIs, npaj, premixed pub thiab pub additives.Raws li Provincial Technical Center, Veyong tau tsim ib qho kev tsim kho tshiab R&D rau cov tshuaj kho tsiaj tshiab, thiab yog lub teb chaws paub txog kev tsim kho tshiab raws li kws kho tsiaj, muaj 65 tus kws tshaj lij.Veyong muaj ob lub hauv paus tsim khoom: Shijiazhuang thiab Ordos, uas lub hauv paus Shijiazhuang npog thaj tsam ntawm 78,706 m2, nrog 13 API khoom suav nrog Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, thiab 11 npaj cov kab ntau lawm suav nrog kev txhaj tshuaj, qhov ncauj tshuaj, , premix, bolus, tshuaj tua kab thiab tshuaj tua kab mob, ects.Veyong muab APIs, ntau tshaj 100 tus kheej-daim ntawv npaj, thiab OEM & ODM kev pabcuam.
Veyong tseem ceeb heev rau kev tswj hwm ntawm EHS (Environment, Health & Safety) system, thiab tau txais daim ntawv pov thawj ISO14001 thiab OHSAS18001.Veyong tau teev nyob rau hauv cov kev lag luam tawm tswv yim tawm tswv yim hauv Hebei Xeev thiab tuaj yeem ua kom cov khoom lag luam tas mus li.
Veyong tau tsim ua tiav kev tswj hwm zoo, tau txais daim ntawv pov thawj ISO9001, Tuam Tshoj GMP daim ntawv pov thawj, Australia APVMA GMP daim ntawv pov thawj, Ethiopia GMP daim ntawv pov thawj, Ivermectin CEP daim ntawv pov thawj, thiab dhau US FDA tshuaj xyuas.Veyong muaj pab pawg tshaj lij ntawm kev sau npe, kev muag khoom thiab kev pabcuam, peb lub tuam txhab tau txais kev cia siab thiab kev txhawb nqa los ntawm ntau tus neeg siv khoom los ntawm cov khoom lag luam zoo, kev muag khoom zoo thiab kev pabcuam tomqab muag, kev tswj xyuas thiab kev tshawb fawb.Veyong tau ua kev koom tes ntev nrog ntau lub tuam txhab kev lag luam tsiaj paub thoob ntiaj teb nrog cov khoom xa tawm mus rau Tebchaws Europe, South America, Middle East, Africa, Asia, thiab lwm yam ntau tshaj 60 lub teb chaws thiab cheeb tsam.
