20% Albendazole Granule
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Pharmacology
Albendazole yog benzimidazole derivative, uas tuaj yeem hloov pauv sai hauv lub cev rau sulfoxide, sulfone cawv thiab 2-aminosulfone cawv.Nws xaiv thiab irreversibly inhibits lub polymerization ntawm cytoplasmic microtubule system ntawm cov cab cab plab hnyuv phab ntsa rau cov plab hnyuv nematodes, uas tuaj yeem thaiv kev nqus thiab nqus ntawm ntau cov as-ham thiab qabzib, ua rau kom qaug zog ntawm endogenous glycogen hauv cov kab, thiab inhibit fumarate reductase Lub kaw lus tiv thaiv kev tsim cov adenosine triphosphate thiab cuam tshuam kev ciaj sia thiab kev tsim tawm ntawm cov cab.Zoo ib yam li mebendazole, cov khoom no kuj tuaj yeem ua rau degeneration ntawm cytoplasmic microtubules ntawm cov kab mob hauv plab hnyuv, thiab khi rau nws cov tubulin, ua rau txhaws ntawm intracellular thauj, ua rau tsub zuj zuj ntawm Golgi endocrine granules, cytoplasmic gradual dissolution, thiab ua tiav degeneration ntawm absorption. hlwb.Ua rau tus kab mob tuag.20% Albendazole granuletuaj yeem tua cov qe qe thiab cov qe qe qe thiab ib nrab tua cov qe qe qe.Ntxiv nrog rau kev tua thiab tshem tawm ntau yam nematodes uas muaj kab mob cab hauv cov tsiaj, nws kuj muaj qhov pom tseeb tua thiab tshem tawm cov teebmeem ntawm tapeworms thiab cysticercus.
Toxicology
Kev ntsuam xyuas toxicological qhia tias cov khoom no muaj toxicity tsawg thiab muaj kev nyab xeeb.Qhov ncauj LD50 rau cov nas yog ntau dua 800mg / kg, thiab qhov siab tshaj plaws rau cov dev yog tshaj 400mg / kg.Cov tshuaj no tsis muaj kev cuam tshuam rau kev ua me nyuam ntawm txiv neej nas, thiab tsis muaj teratogenic cuam tshuam rau poj niam nas.Kev nqus ntawm fetal tuaj yeem tshwm sim thaum koob tshuaj ntau dua [30 mg / (㎏·hnub)] siv rau poj niam nas thiab poj niam luav.Thiab skeletal deformities.
Kev siv thiab siv
Raws li albendazole.Kev tswj qhov ncauj: ib zaug, 25 ~ 50mg / kg lub cev hnyav.Los yog ua raws li tus kws kho mob cov lus qhia.
Kev Phem Tsis Zoo
(1) thaum cov dev tau muab 50 mg / kg ob zaug ib hnub, lawv yuav maj mam tsim anorexia
(2) Kev siv albendazole thaum ntxov cev xeeb tub tuaj yeem nrog teratogenicity thiab embryotoxicity.
Nco tseg
Cov tsiaj yuav tsum ceev faj thawj 45 hnub tom qab cev xeeb tub
Hebei Veyong kws tshuaj Co., Ltd, tau tsim nyob rau hauv 2002, nyob rau hauv Shijiazhuang City, Hebei xeev, Tuam Tshoj, ib sab ntawm lub peev Beijing.Nws yog ib lub tuam txhab loj GMP-certified veterinary tshuaj lag luam, nrog R & D, ntau lawm thiab muag khoom ntawm veterinary APIs, npaj, premixed pub thiab pub additives.Raws li Provincial Technical Center, Veyong tau tsim ib qho kev tsim kho tshiab R&D rau cov tshuaj kho tsiaj tshiab, thiab yog lub teb chaws paub txog kev tsim kho tshiab raws li kws kho tsiaj, muaj 65 tus kws tshaj lij.Veyong muaj ob lub hauv paus tsim khoom: Shijiazhuang thiab Ordos, uas lub hauv paus Shijiazhuang npog thaj tsam ntawm 78,706 m2, nrog 13 API khoom suav nrog Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, thiab 11 npaj cov kab ntau lawm suav nrog kev txhaj tshuaj, qhov ncauj tshuaj, , premix, bolus, tshuaj tua kab thiab tshuaj tua kab mob, ects.Veyong muab APIs, ntau tshaj 100 tus kheej-daim ntawv npaj, thiab OEM & ODM kev pabcuam.
Veyong tseem ceeb heev rau kev tswj hwm ntawm EHS (Environment, Health & Safety) system, thiab tau txais daim ntawv pov thawj ISO14001 thiab OHSAS18001.Veyong tau teev nyob rau hauv cov kev lag luam tawm tswv yim tawm tswv yim hauv Hebei Xeev thiab tuaj yeem ua kom cov khoom lag luam tas mus li.
Veyong tau tsim ua tiav kev tswj hwm zoo, tau txais daim ntawv pov thawj ISO9001, Tuam Tshoj GMP daim ntawv pov thawj, Australia APVMA GMP daim ntawv pov thawj, Ethiopia GMP daim ntawv pov thawj, Ivermectin CEP daim ntawv pov thawj, thiab dhau US FDA tshuaj xyuas.Veyong muaj pab pawg tshaj lij ntawm kev sau npe, kev muag khoom thiab kev pabcuam, peb lub tuam txhab tau txais kev cia siab thiab kev txhawb nqa los ntawm ntau tus neeg siv khoom los ntawm cov khoom lag luam zoo, kev muag khoom zoo thiab kev pabcuam tomqab muag, kev tswj xyuas thiab kev tshawb fawb.Veyong tau ua kev koom tes ntev nrog ntau lub tuam txhab kev lag luam tsiaj paub thoob ntiaj teb nrog cov khoom xa tawm mus rau Tebchaws Europe, South America, Middle East, Africa, Asia, thiab lwm yam ntau tshaj 60 lub teb chaws thiab cheeb tsam.
