250mg triclabendazole bolus
.png)
.png)
.png)
.png)
Kws pharactricological ua
Pharmacodynynics briclobendazole benzimidAmidazole chav kawm ntawm cov tshuaj fas fas fas fas fas fas fas fas fas fas fas fasciola ntawm ntau lub hnub nyoog. Fluke tshuaj. Tom qab cov tshuaj yog nqus tau, nws cuam tshuam nrog microlotubuel qauv thiab ua haujlwm ntawm cov parasite, interhibits qhov kev tso tawm ntawm cov kev tiv thaiv parasite hydrolytic. Cov nyhuv ntawm Triclobendazole ntawm cov cab yuav txawv nrog cov concentration, xws li cov neeg laus ntawm cov kev sib xyaw qis (1 ~ 3μg / ml)
Cov tshuaj tseem muaj sia nyob rau 24 teev, thiab kev ua haujlwm tsis muaj zog nyob rau hauv qhov siab dua (10-25μg / ml) rau 24 teev; Lub siab siab ntawm 25-50G / ML cov me nyuam initionhit nws tau 24 teev. Tab sis ntau rhiab rau cov cab. Thaum muaj 10 μg / ml, txhua qhov kev ua 24-teev yog inhibited.
Pharmaconinetics
Lub xyoob bioavailability ntawm triclobendazole yog siab. Tom qab kev tswj hwm ntawm qhov ncauj ntawm 10 mg / kg lub cev nyhav hauv cov tshis thiab yaj, cov ntshav ntawm triclobendazole thiab nws cov ntshav tau ntau dua. Lub ncov ntawm cov tshuaj yog 5 txog 20 zaug ntawm lwm benzimidazole anthelmintics, thiab kev tshem tawm ib nrab-lub neej yog li 22 teev. Triclobendazole nyob rau hauv yaj thiab nas rau sulfone thiab sulfoxide derivatives, uas khi rau albumin thiab kev ua tsis tu ncua hauv ntshav ntau dua 7 hnub. High ntshav siab thiab khi rau cov ntshav siab albumin tshwm sim cuam tshuam nrog ntev ntev ntawm kev ua ntawm antifascioli. Tom qab 10 hnub ntawm kev tswj hwm cov yaj, kwv yees li 95% ntawm cov tshuaj tau tawm hauv cov zis, thiab pub tsawg dua 1% yog excreted hauv cov mis.
Kev ua thiab siv
Benzimidazole Anti-Fasciola Yeeb Tshuaj. Nws yog tsuas yog siv rau kev tiv thaiv thiab kev kho mob fasciola hepatica kis tus mob hauv cov nyuj thiab yaj.
Cov tshuaj tiv thaiv tsis zoo
Tsis muaj kev cuam tshuam tau tshwm sim thaum siv raws li siv raws li kev siv thiab ntau npaum li cas
Cov kev ceev faj
(1) Xiam rau thaum lub sijhawm siv mis.
(2) Nws yog kev lom zem heev rau ntses, thiab cov xiav tshuaj uas tseem tshuav yuav tsum tsis ua paug dej.
(3) Cov neeg uas ua xua rau cov tshuaj yuav tsum zam kev sib chwv tawv nqaij thiab siv hnab looj tes thaum noj cov tshuaj, thiab kev txwv tsis pub noj, haus thiab haus luam yeeb.
(4) ntxuav tes tom qab thov
Rho tawm lub sijhawm
56 hnub rau nyuj thiab yaj
Chaw ntim khoom
Khaws rau hauv qhov chaw hauv qab no 30 ℃.
Heii Veyong Kws Tshuaj Co., Ltd, tau tsim tsa hauv xyoo 2002, nyob hauv Shijiazhuang nroog, Hebei Xeev, Suav, ib sab ntawm lub peev Beijing. Nws yog ib qho loj GMP-lees paub cov kws kho tsiaj siv tshuaj kho, nrog R & D, ntau lawm thiab kev muag khoom ntawm cov kws kho tsiaj kho mob thiab pub zaub mov noj thiab pub ntxiv. Raws li Pretincial Technical Center, VeYong tau tsim ib qho kev tsim kho tshiab R & D qhov tsim kho tshiab ua haujlwm raws cov kws kho tsiaj tsim kho kom zoo nkauj, muaj 65 tus kws tshaj lij kev ua haujlwm. Veyong muaj ob lub hauv paus ntau lawm: shijiazhuang thiab ordos, thiab 11 aprinomection ecotharate ecothuang, hmoov, premix, bolus, tshuaj tua kab thiab tshuaj tua kab mob, ects. Veyong muab APIs, ntau dua 100 tus kheej npaj, thiab OEM & ODM kev pabcuam.
Veyong txuas qhov tseem ceeb rau kev tswj hwm ntawm EHS (ib puag ncig & kev nyab xeeb) system, thiab tau txais ISO14001 thiab OHSAS18001 daim ntawv pov. Veyong tau teev nyob rau hauv cov tswv yim tawm kev lag luam muaj kev lag luam hauv Hebi xeev thiab tuaj yeem ua kom cov khoom lag luam txuas ntxiv.
Veyong tsim cov txheej txheem tswj hwm zoo, tau txais ISO9001 Daim Ntawv Pov Thawj GMP, Australia GMP Daim Ntawv Pov Thawj, Tebchaws Australia, Tebchaws Asmeskas Kev Tshawb Xyuas FDA. Veyong muaj cov pab pawg tshaj lij ntawm kev sau npe, kev lag luam thiab kev txhawb nqa los ntawm ntau cov khoom lag luam zoo, muaj kev pab cuam ua ntej thiab kev tswj hwm tom qab kev tshawb fawb. Veyong tau ua haujlwm ntev ntev nrog ntau cov khoom lag luam hauv nroog, South America, Tebchaws Asmeskas, thiab lwm yam Ntau tshaj 60 lub tebchaws thiab cheeb tsam.
