20% Florfenicol WSP
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Video
Pharmacodynamics
Florfenicol yog ib tug dav-spectrum amide cawv tshuaj tua kab mob thiab ib tug bacteriostatic tus neeg sawv cev, uas ua los ntawm inhibiting lub synthesis ntawm cov kab mob proteins los ntawm khi rau 50S subunit ntawm lub ribosome.Nws muaj zog tiv thaiv kab mob tiv thaiv ntau yam kab mob gram-positive thiab gram-negative kab mob.Pasteurella hemolytica, Pasteurella multocida, thiab Actinobacillus pleuropneumoniae yog qhov muaj feem cuam tshuam rau florfenicol.Cov tshuaj tua kab mob ntawm florfenicol tiv thaiv ntau cov kab mob hauv vitro zoo ib yam li lossis muaj zog dua li ntawm thiamphenicol, thiab qee cov kab mob uas tiv taus amide cawv vim acetylation, xws li Escherichia coli thiab Klebsiella pneumoniae, tej zaum tseem yuav rhiab heev rau florfenicol.
Nws yog tsuas yog siv rau cov kab mob ntawm cov npua, qaib thiab ntses los ntawm cov kab mob rhiab heev, xws li cov kab mob ua pa ntawm nyuj thiab npua los ntawm Pasteurella hemolytica, Pasteurella multocida thiab Actinobacillus pleuropneumoniae.typhoid fever thiab paratyphoid fever tshwm sim los ntawm Salmonella, qaib cholera, pullorum, Escherichia coli, thiab lwm yam.ntses kab mob tshwm sim los ntawm Pasteurella, Vibrio, Staphylococcus aureus, Hydromonas, Enteritidis, thiab lwm yam Sepsis, enteritis, kab mob ntawm daim tawv nqaij liab, thiab lwm yam.
Pharmacokinetics
Kev tswj hwm qhov ncauj ntawm florfenicol yog nqus tau sai, thiab kev kho mob tuaj yeem ncav cuag hauv cov ntshav tom qab li 1 teev, thiab cov ntshav siab siab tuaj yeem ncav cuag hauv 1 mus rau 3 teev.Lub bioavailability yog tshaj 80%.Florfenicol yog dav faib nyob rau hauv cov tsiaj thiab yuav kis tau los ntawm cov ntshav-hlwb barrier.Nws yog tsuas yog excreted nyob rau hauv thawj daim ntawv los ntawm cov zis, thiab ib tug me me npaum li cas yog excreted nrog cov quav.
Cov tshuaj sib cuam tshuam
(1) Macrolides thiab lincosamides muaj tib lub hom phiaj ntawm kev ua raws li cov khoom no, lawv ob leeg raug khi rau 50S subunit ntawm cov kab mob ribosome, thiab tuaj yeem tsim kev sib nrig sib antagonism thaum siv ua ke.(2) Nws tuaj yeem tiv thaiv cov kab mob bactericidal ntawm penicillins lossis aminoglycosides, tab sis nws tsis tau pom hauv cov tsiaj.
Kev ua thiab siv
Amide cawv tshuaj tua kab mob.Rau cov kab mob Pasteurella thiab Escherichia coli.
Kev siv thiab siv
Raws li cov khoom no.Kev tswj qhov ncauj: ib 1kg lub cev hnyav, 0.1 ~ 0.15g rau npua thiab qaib.2 zaug hauv ib hnub rau 3 mus rau 5 hnub.Ntses 50 ~ 75mg.1 zaug hauv ib hnub rau 3 mus rau 5 hnub.
Kev phiv tshuaj
20% Florfenicol dej soluble hmoov muaj qee yam kev tiv thaiv kab mob thaum siv ntau dua li cov koob tshuaj pom zoo.
Nco ntsoov
(1) Cov qaib uas nteg qe rau tib neeg noj yuav tsum tsis txhob siv thaum lub sij hawm tso qe;(2) Siv ceev faj hauv cov neeg yug tsiaj.Nws muaj embryotoxicity thiab yuav tsum tau siv nrog ceev faj nyob rau hauv cev xeeb tub thiab lactating tsiaj nyeg;(3) Nws yog contraindicated thaum txhaj tshuaj tiv thaiv lossis hauv cov tsiaj uas muaj kev tiv thaiv kab mob hnyav;(4) Hauv cov tsiaj uas muaj lub raum tsis txaus, cov koob tshuaj yuav tsum raug txo kom tsim nyog lossis ncua sijhawm noj tshuaj.
Lub sijhawm rho nyiaj
20 hnub rau npua, 5 hnub rau qaib;375 degree hnub rau ntses.
Cia
Khaws kaw thiab nyob rau hauv qhov chaw qhuav
Hebei Veyong kws tshuaj Co., Ltd, tau tsim nyob rau hauv 2002, nyob rau hauv Shijiazhuang City, Hebei xeev, Tuam Tshoj, ib sab ntawm lub peev Beijing.Nws yog ib lub tuam txhab loj GMP-certified veterinary tshuaj lag luam, nrog R & D, ntau lawm thiab muag khoom ntawm veterinary APIs, npaj, premixed pub thiab pub additives.Raws li Provincial Technical Center, Veyong tau tsim ib qho kev tsim kho tshiab R&D rau cov tshuaj kho tsiaj tshiab, thiab yog lub teb chaws paub txog kev tsim kho tshiab raws li kws kho tsiaj, muaj 65 tus kws tshaj lij.Veyong muaj ob lub hauv paus tsim khoom: Shijiazhuang thiab Ordos, uas lub hauv paus Shijiazhuang npog thaj tsam ntawm 78,706 m2, nrog 13 API khoom suav nrog Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, thiab 11 npaj cov kab ntau lawm suav nrog kev txhaj tshuaj, qhov ncauj tshuaj, , premix, bolus, tshuaj tua kab thiab tshuaj tua kab mob, ects.Veyong muab APIs, ntau tshaj 100 tus kheej-daim ntawv npaj, thiab OEM & ODM kev pabcuam.
Veyong tseem ceeb heev rau kev tswj hwm ntawm EHS (Environment, Health & Safety) system, thiab tau txais daim ntawv pov thawj ISO14001 thiab OHSAS18001.Veyong tau teev nyob rau hauv cov kev lag luam tawm tswv yim tawm tswv yim hauv Hebei Xeev thiab tuaj yeem ua kom cov khoom lag luam tas mus li.
Veyong tau tsim ua tiav kev tswj hwm zoo, tau txais daim ntawv pov thawj ISO9001, Tuam Tshoj GMP daim ntawv pov thawj, Australia APVMA GMP daim ntawv pov thawj, Ethiopia GMP daim ntawv pov thawj, Ivermectin CEP daim ntawv pov thawj, thiab dhau US FDA tshuaj xyuas.Veyong muaj pab pawg tshaj lij ntawm kev sau npe, kev muag khoom thiab kev pabcuam, peb lub tuam txhab tau txais kev cia siab thiab kev txhawb nqa los ntawm ntau tus neeg siv khoom los ntawm cov khoom lag luam zoo, kev muag khoom zoo thiab kev pabcuam tomqab muag, kev tswj xyuas thiab kev tshawb fawb.Veyong tau ua kev koom tes ntev nrog ntau lub tuam txhab kev lag luam tsiaj paub thoob ntiaj teb nrog cov khoom xa tawm mus rau Tebchaws Europe, South America, Middle East, Africa, Asia, thiab lwm yam ntau tshaj 60 lub teb chaws thiab cheeb tsam.
