0.2% IVERMECTIN DRENCH
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Pharmacological kev ua
IvermectinFeem ntau muaj cov nyhuv anthelmintic zoo ntawm nematodes thiab nto arthropods hauv vivo.Nws cov txheej txheem anthelmintic yog los txhawb kev tso tawm ntawm γ-aminobutyric acid (GABA) los ntawm presynaptic neurons, yog li qhib GABA-mediated chloride channels.Ivermectin kuj tseem xaiv thiab muaj kev sib raug zoo rau glutamate-mediated chloride channels nyob ze GABA-mediated sites hauv invertebrate paj hlwb thiab cov leeg hlwb, yog li cuam tshuam nrog cov teeb liab kis ntawm cov leeg neuromuscular thiab so kom txaus thiab tuag tes tuag taw, ua rau cov kab mob tuag lossis tshem tawm ntawm cov lub cev.Cov inhibitory interneurons thiab excitatory motoneurons ntawm C. elegans yog lawv qhov chaw ntawm kev txiav txim, thaum lub site ntawm kev txiav txim ntawm arthropods yog lub neuromuscular hlws ris.Nws tseem muaj txiaj ntsig zoo tiv thaiv arthropods, xws li yoov maggots, mites, thiab ntshauv.Cov neeg laus Coronaria dentata thiab cov kab mob tsis paub qab hau hauv npua, kuj tseem zoo heev rau Trichinella spiralis hauv txoj hnyuv (tsis zoo rau intramuscular Trichinella spiralis), thiab tseem muaj kev tswj xyuas zoo ntawm cov ntshauv thiab Sarcoptes scabiei.Nws tsis muaj txiaj ntsig tiv thaiv trematodes thiab tapeworms.
Pharmacokinetics
Pharmacokinetics ntawmsiv ivermectinNws txawv nyob ntawm seb hom tsiaj, daim ntawv npaum li cas, thiab txoj kev tswj hwm.Lub bioavailability ntawm kev txhaj tshuaj subcutaneous yog siab dua li kev tswj hwm qhov ncauj, tab sis kev tswj qhov ncauj yog nqus sai dua li kev txhaj tshuaj subcutaneous.Tom qab nqus tau, nws tuaj yeem faib tau zoo rau feem ntau cov ntaub so ntswg, tab sis nws tsis yooj yim rau nkag mus rau hauv cov kua cerebrospinal.Qhov pom meej ntim ntawm kev faib tawm hauv yaj thiab npua yog 4.6 thiab 4 L / kg, feem.Nws muaj ib nrab-lub neej ntev nyob rau hauv feem ntau cov tsiaj, 2 mus rau 7 thiab 0.5 hnub nyob rau hauv yaj thiab npua, feem.Cov khoom no yog metabolized nyob rau hauv daim siab, feem ntau hydroxylated nyob rau hauv yaj, thiab mas methylated nyob rau hauv npua.Nws yog tsuas yog tawm hauv cov quav thiab tsawg dua 5% raug tshem tawm tsis hloov lossis ua cov metabolites hauv cov zis.Nyob rau hauv lactating dams, 5% ntawm cov koob tshuaj yog tawm hauv cov mis nyuj.
Cov tshuaj sib cuam tshuam
Kev siv sib xyaw nrog diethylcarbamazine tuaj yeem ua rau mob hnyav lossis tuag taus.
Kev ua thiab siv
Macrolide antiparasitic tshuaj.Siv rau kev tswj cov nematode, acariasis thiab kab mob cab kab mob hauv yaj thiab npua.
Dosage thiab kev tswj hwm
Qhov ncauj: ib koob, 0.1 ml rau yaj thiab 0.15 ml rau npua ib 1 kg ntawm lub cev hnyav.
Kev phiv tshuaj
Tsis muaj kev phiv tshwm sim thaum siv raws li kev siv thiab ntau npaum li cas.
Cov kev ceev faj
(1) Nws yog contraindicated thaum lactation.
(2) Nws yuav tsum tau siv nrog ceev faj nyob rau hauv sows thaum thawj 45 hnub ntawm cev xeeb tub.
(3) Ivermectin cws, ntses thiab cov kab mob hauv dej yog cov tshuaj lom heev, thiab ntim thiab ntim cov tshuaj seem yuav tsum tsis txhob muaj dej paug.
Lub sijhawm rho nyiaj: 35 hnub rau yaj thiab 28 hnub rau npua.
Lub sijhawm rho nyiaj
35 hnub rau yaj thiab 28 hnub rau npua.
Hebei Veyong kws tshuaj Co., Ltd, tau tsim nyob rau hauv 2002, nyob rau hauv Shijiazhuang City, Hebei xeev, Tuam Tshoj, ib sab ntawm lub peev Beijing.Nws yog ib lub tuam txhab loj GMP-certified veterinary tshuaj lag luam, nrog R & D, ntau lawm thiab muag khoom ntawm veterinary APIs, npaj, premixed pub thiab pub additives.Raws li Provincial Technical Center, Veyong tau tsim ib qho kev tsim kho tshiab R&D rau cov tshuaj kho tsiaj tshiab, thiab yog lub teb chaws paub txog kev tsim kho tshiab raws li kws kho tsiaj, muaj 65 tus kws tshaj lij.Veyong muaj ob lub hauv paus tsim khoom: Shijiazhuang thiab Ordos, uas lub hauv paus Shijiazhuang npog thaj tsam ntawm 78,706 m2, nrog 13 API khoom suav nrog Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, thiab 11 npaj cov kab ntau lawm suav nrog kev txhaj tshuaj, qhov ncauj tshuaj, , premix, bolus, tshuaj tua kab thiab tshuaj tua kab mob, ects.Veyong muab APIs, ntau tshaj 100 tus kheej-daim ntawv npaj, thiab OEM & ODM kev pabcuam.
Veyong tseem ceeb heev rau kev tswj hwm ntawm EHS (Environment, Health & Safety) system, thiab tau txais daim ntawv pov thawj ISO14001 thiab OHSAS18001.Veyong tau teev nyob rau hauv cov kev lag luam tawm tswv yim tawm tswv yim hauv Hebei Xeev thiab tuaj yeem ua kom cov khoom lag luam tas mus li.
Veyong tau tsim ua tiav kev tswj hwm zoo, tau txais daim ntawv pov thawj ISO9001, Tuam Tshoj GMP daim ntawv pov thawj, Australia APVMA GMP daim ntawv pov thawj, Ethiopia GMP daim ntawv pov thawj, Ivermectin CEP daim ntawv pov thawj, thiab dhau US FDA tshuaj xyuas.Veyong muaj pab pawg tshaj lij ntawm kev sau npe, kev muag khoom thiab kev pabcuam, peb lub tuam txhab tau txais kev cia siab thiab kev txhawb nqa los ntawm ntau tus neeg siv khoom los ntawm cov khoom lag luam zoo, kev muag khoom zoo thiab kev pabcuam tomqab muag, kev tswj xyuas thiab kev tshawb fawb.Veyong tau ua kev koom tes ntev nrog ntau lub tuam txhab kev lag luam tsiaj paub thoob ntiaj teb nrog cov khoom xa tawm mus rau Tebchaws Europe, South America, Middle East, Africa, Asia, thiab lwm yam ntau tshaj 60 lub teb chaws thiab cheeb tsam.
